Ethyl 2-(4-formylphenoxy)acetate → Acetic acid, 2-(4-formylphenoxy)-

HRID 592079Notes

Reaction equation

HRID 592079 reaction equation
[CH:1]([C:3]1[CH:15]=[CH:14][C:6]([O:7][CH2:8][C:9]([O:11]CC)=[O:10])=[CH:5][CH:4]=1)=[O:2].C(C1C=C(C=CC=1)OCC(O)=O)=O>>[CH:1]([C:3]1[CH:15]=[CH:14][C:6]([O:7][CH2:8][C:9]([OH:11])=[O:10])=[CH:5][CH:4]=1)=[O:2]

Participants

3

Reactant 2

HCID 291358Ethyl 2-(4-formylphenoxy)acetateHCID 6018952-(3-Formylphenoxy)acetic acid

Product 1

HCID 89177Acetic acid, 2-(4-formylphenoxy)-Yield 57%

Procedure

Ethyl 2-(4-formylphenoxy)acetate (52) was treated in an analogous manner to compound 48 to yield the desired product (57%) as a white solid. NMR: δ 4.834 (s, 2H), 7.112 (d, J=7.2 Hz, 2H), 7.866 (d, J=7.6 Hz, 2H), 9.878 (s, 1H), 13.146 (s, 1H).

Sources & evidence

ORD record
ord-d2b3ba8f4f444c928787ce77a5c9bf23
Source dataset
uspto-grants-2016_01
Patent number
US09238656B2

Reaction notes

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