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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 592081Generated: November 1, 2026

3-(2-Oxo-2-(piperazin-1-yl)ethoxy)benzaldehyde → 4-(2-Oxo-2-(piperazin-1-yl)ethoxy)benzaldehyde

https://huagongshe.com/reaction/592081

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2-Oxo-2-(piperazin-1-yl)ethoxy)benzaldehydeHCID 89726202—
ReactantTert-Butyl 4-(2-(4-formylphenoxy)acetyl)piperazine-1-carboxylateHCID 89738600—
Product4-(2-Oxo-2-(piperazin-1-yl)ethoxy)benzaldehydeHCID 3916217760%

Reaction Steps

tert-Butyl 4-(2-(4-formylphenoxy)acetyl)piperazine-1-carboxylate (54) was treated in an analogous manner to compound 50 to yield the desired product (60%) as a pale yellow solid. LCMS: 97% (M++1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09238656B2
Source datasetuspto-grants-2016_01
ORD IDord-4a40b16a70194b62bfde025818915928
Source noteuspto-grants-2016_01