HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 89726233, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | tert-Butyl 4-(3-formylphenoxy)piperidine-1-carboxylate | HCID 53439173 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 89726233 | HCID 89726233 | — |
Reaction Steps
tert-butyl 4-(3-formylphenoxy)piperidine-1-carboxylate (61) (5.55 mmol) was taken in DCM and cooled to 0° C. when TFA (5 ml) was added drop wise and then stirred at rt for 16 h when TLC confirmed completion of reaction. The reaction mixture was concentrated and used directly for the next step. White solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09238656B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-3a4fccb6708048f1a3076f438139c3ae |
| Source note | uspto-grants-2016_01 |