反应详情

1.2 g (0.005 mol) of 6-acetylbenzoselenazolinone are introduced together with 7.5 cm3 of 3% sodium hydroxide into a ground-necked round-bottom flask cooled in an ice bath. 0.38 g (0.001 mol) of sodium borohydride is then added slowly and with stirring. The solution is stirred at room temperature for 15 hours an the acidified with aqueous hydrochloric acid solution diluted 4-fold. The precipitate obtained is drained, washed with water and then recrystallized in a mixture of cyclohexane (1/3) and ethyl acetate (2/3).

1. temperaturecooled in an ice bath
2. stirringThe solution is stirred at room temperature for 15 hours an the
3. additiondiluted 4-fold
4. customThe precipitate obtained
5. washwashed with water
6. customrecrystallized in a mixture of cyclohexane (1/3) and ethyl acetate (2/3)