HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azobisisobutyronitrile → Methyl 2-(4-bromomethylphenoxy)-2-(2-chlorophenyl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azobisisobutyronitrile | HCID 6547 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | Methyl 2-(2-chlorophenyl)-2-(4-methylphenoxy)acetate | HCID 19385716 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | Methyl 2-(4-bromomethylphenoxy)-2-(2-chlorophenyl)acetate | HCID 19385740 | 73% |
Reaction Steps
A solution of the product of Example 3, Step B (0.2 g, 0.69 mmol), N-bromosuccinimide (117 mg, 166 mmol) and a catalytic amount of AIBN in 2 ml CCl4 was refluxed for 30 minutes. The reaction mixture was concentrated in vacuo and chromatographed on silica gel (125×20 mm) eluting with 5% ethyl acetate in hexane. The product was isolated in a 73% yield (186 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05246944 |
| Source dataset | uspto-grants-1993_09 |
| ORD ID | ord-52fd80fbaf8b482ba702acb847f8a77a |
| Source note | uspto-grants-1993_09 |