HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-nitropyridine → HCID 86683703, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-nitropyridine | HCID 817620 | — |
| Reactant | Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate | HCID 11243758 | — |
| Reactant | tert-butyl (2R,5S)-2,5-dimethylpiperazine-1-carboxylate | HCID 24903576 | — |
| Product | HCID 86683703 | HCID 86683703 | 75% |
Reaction Steps
Following the procedures as described for compound 101g, (2R,5S)-tert-butyl-2,5-dimethylpiperazine-1-carboxylate (1.5 g, 6.0 mmol), and 5-bromo-2-nitropyridine (1212 mg, 6.0 mmol) were reacted to give 122a as a yellow solid (1500 mg, 75%). LCMS: [M+H]+ 337
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09238655B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-45ad26e2e8af471a8e6822f9207d7739 |
| Source note | uspto-grants-2016_01 |