HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminopropionitrile → HCID 86684614, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminopropionitrile | HCID 1647 | — |
| Reactant | 5-(2-Methoxyethyl)-2-nitro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine | HCID 86683990 | — |
| Product | HCID 86684614 | HCID 86684614 | 81.4% |
Reaction Steps
Following the procedure of Example 296d, and starting with 1-(2-bromoethyl)-5-(chloromethyl)-3-nitro-1H-pyrazole 296d (268 mg, 1.00 mmol) and 3-aminopropanenitrile (210 mg, 3.00 mmol) afforded 338a as a white solid (180 mg, 81%). MS-ESI: [M+H]+ 222.1
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09238655B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-77d3f6bcbbc74a4abe917c5747a8b471 |
| Source note | uspto-grants-2016_01 |