HCID 131734558, compound → Calcium di(L-lysinate)

HRID 593228Notes

Reaction equation

HRID 593228 reaction equation
O.[NH2:2][C@H:3]([C:9]([O-:11])=[O:10])[CH2:4][CH2:5][CH2:6][CH2:7][NH2:8].[NH2:12][C@H:13]([C:19]([O-:21])=[O:20])[CH2:14][CH2:15][CH2:16][CH2:17][NH2:18].[Ca+2:22]>CO>[NH2:2][C@H:3]([C:9]([O-:11])=[O:10])[CH2:4][CH2:5][CH2:6][CH2:7][NH2:8].[NH2:12][C@H:13]([C:19]([O-:21])=[O:20])[CH2:14][CH2:15][CH2:16][CH2:17][NH2:18].[Ca+2:22]

Participants

3

Reactant 1

HCID 131734558HCID 131734558, compound

Product 1

HCID 6454211Calcium di(L-lysinate)Yield 197.3%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

A stirred solution of calcium bis-lysinate monohydrate (1.92 g, 5.0 mmol) in methanol (10 mL) was treated with a solution of EPA (1.55 g, 5.125 mmol) in methanol (10 mL) and stirred for 15 min, then concentrated in vacuo to a pale yellow foam. The above foam was triturated from acetonitrile (20 mL) and dried in vacuo to afford 3.26 g (97%) of subject material as a pale yellow powder.

Workup

  1. concentrationconcentrated in vacuo to a pale yellow foam
  2. customThe above foam was triturated from acetonitrile (20 mL)
  3. customdried in vacuo

Sources & evidence

ORD record
ord-a3d804495e12465fbeb79b95112db4ed
Source dataset
uspto-grants-2016_01
Patent number
US09242008B2

Reaction notes

Loading…