Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sulfanilamide | HCID 5333 | — |
| Reactant | 2-Fluoro-4-iodopyridine | HCID 7023570 | — |
| Solvent | Acetonitrile--water (1/1) | HCID 18373917 | — |
| Product | HCID 68287865 | HCID 68287865 | — |
Reaction Steps
A mixture of 2-fluoro-4-iodopyridine (1.0 g, 4.48 mmol) and 4-aminobenzenesulfonamide (772 mg, 4.48 mmol) was heated with an oil bath for 3 hours at 150° C. The title compound A4 was obtained from the residue by preparative HPLC (water/ACN gradient). Yield: 135 mg (8%). MS (ES) C11H10IN3O2S requires: 375. found: 376 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09242937B2 |
|---|
| Source dataset | uspto-grants-2016_01 |
|---|
| ORD ID | ord-a826135d60454f5ebeda7e3fbd3c336c |
|---|
| Source note | uspto-grants-2016_01 |
|---|
