反应详情

To a solution of C2 (98 mg, 0.29 mmol) in THF/MeOH 1:1 (20 mL) was added Pd/C (10% w/w, 46 mg). The reaction mixture was stirred under hydrogen atmosphere (1 atm) at RT for 15 hours. The suspension was filtered through a pad of Celite® and the solvent was removed in vacuo to leave the desired product I1 as a brown solid (89 mg, 99%). MS (ES) C18H16FN3O requires: 309. found: 310 (M+H)+.

1. filtrationThe suspension was filtered through a pad of Celite®
2. customthe solvent was removed in vacuo