HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 2-Fluoro-4-(trifluoromethyl)benzoyl isocyanate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 2-Fluoro-4-(trifluoromethyl)benzamide | HCID 605689 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | 2-Fluoro-4-(trifluoromethyl)benzoyl isocyanate | HCID 90019717 | — |
Reaction Steps
The title compound was prepared according to the procedure described in step-2 of Intermediate-8 by using 2-fluoro-4-(trifluoromethyl)benzamide (0.200 g, 0.96 mmol), EDC (10 mL) and oxalyl chloride (0.1 mL, 1.15 mmol) to afford 0.200 g of the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09439890B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-70a41fa265ea4ec0ad3939d56ba4abb6 |
| Source note | uspto-grants-2016_09 |