HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 3-((2,2,2-Trifluoroacetamido)methyl)-2,6-dimethylbenzoyl isocyanate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 3-((2,2,2-Trifluoroacetamido)methyl)-2,6-dimethylbenzamide | HCID 90019133 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | 3-((2,2,2-Trifluoroacetamido)methyl)-2,6-dimethylbenzoyl isocyanate | HCID 90019298 | — |
Reaction Steps
The title compound was prepared according to the procedure described in step-2 of Intermediate-8 by using 3-((2,2,2-trifluoroacetamido)methyl)-2,6-dimethylbenzamide (1.0 g, 3.6 mmol), oxalyl chloride and EDC (10 mL) to afford 0.900 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09439890B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-5ff782c0471f46efab3756600b21d4dd |
| Source note | uspto-grants-2016_09 |