HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pivaloyl chloride → N-(3-amino-4-chlorobenzyl)pivalamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pivaloyl chloride | HCID 62493 | — |
| Reactant | 5-(Aminomethyl)-2-chloroaniline | HCID 13465097 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N-(3-amino-4-chlorobenzyl)pivalamide | HCID 66765386 | — |
Reaction Steps
The title compound was prepared according to the procedure described in step-2 of Intermediate-83 by using 5-(aminomethyl)-2-chlorobenzenamine (2.0 g), pivaloyl chloride (0.2 mL), TEA (2 mL) and THF (10 mL) to afford 2.0 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09439890B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-a8099ef99c6b4d1a898bda7d09d150ba |
| Source note | uspto-grants-2016_09 |