HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 4-Fluoro-3-(trifluoromethyl)benzoyl isocyanate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 4-Fluoro-3-(trifluoromethyl)benzamide | HCID 144254 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | 4-Fluoro-3-(trifluoromethyl)benzoyl isocyanate | HCID 90019295 | — |
Reaction Steps
The title compound was prepared according to the procedure described in step-2 of Intermediate-8 by using 4-fluoro-3-(trifluoromethyl)benzamide (0.200 g), oxalyl chloride (0.012 mL) and EDC (15 mL) to afford 0.150 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09439890B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-f307a7d3412647da9c443a172da55893 |
| Source note | uspto-grants-2016_09 |