HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-2-methylpropane → HCID 89875838, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-2-methylpropane | HCID 6555 | — |
| Reactant | 2-tert-Butyl-1,1,3,3-tetramethylguanidine | HCID 3571581 | — |
| Reactant | HCID 89875960 | HCID 89875960 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 89875838 | HCID 89875838 | 72.4% |
Reaction Steps
The title compound (46.8 mg) was prepared from 4-fluoro-N-(5-isopropyl-3-methoxypyridin-2-yl)benzenesulfonamide (55 mg, 0.170 mmol), 2-(tert-butyl)-1,1,3,3-tetramethylguanidine (0.068 mL, 0.339 mmol) in acetonitrile (4 mL) and 1-bromo-2-methylpropane (0.037 mL, 0.339 mmol) following the procedure described for Example 40. LCMS (2 min, formic) Rt 1.34 min, m/z (ES+) 381 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242972B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-3216795e14cc4f5d8c4958856256f219 |
| Source note | uspto-grants-2016_01 |