HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(2,2'-Bipyridine)-6-carbaldehyde → 1-([2,2'-Bipyridin]-6-ylmethyl)-6-(2,6-dimethoxyphenyl)piperidin-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (2,2'-Bipyridine)-6-carbaldehyde | HCID 11095276 | — |
| Edukt | Methyl 5-amino-5-(2,6-dimethoxyphenyl)pentanoate | HCID 69082713 | — |
| Produkt | 1-([2,2'-Bipyridin]-6-ylmethyl)-6-(2,6-dimethoxyphenyl)piperidin-2-one | HCID 69085730 | — |
Reaktionsschritte
Prepared according to the described general procedure 1 (GP1) by reaction of methyl 5-amino-5-(2,6-dimethoxyphenyl)pentanoate with [2,2′-bipyridine]-6-carbaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.58 min.; [M+H]+: 403.99 g/mol.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09242970B2 |
| Quelldatensatz | uspto-grants-2016_01 |
| ORD ID | ord-cadc240fe5254533860205f63aefa8e5 |
| Quellennotiz | uspto-grants-2016_01 |