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HRID594579

反应详情

EQUATION

反应方程式

HRID 594579 的结构方程式

REACTANTS

反应物

2
结构：FC(F)(F)Oc1ccc(CBr)cc1Cl
HCID2773849

4-(Bromomethyl)-2-chloro-1-(trifluoromethoxy)benzene

C8H5BrClF3O

结构：COc1cccc(OC)c1C1CCCC(=O)N1
HCID69082526

未命名化合物

PRODUCTS

生成物

1
结构：COc1cccc(OC)c1C1CCCC(=O)N1Cc1ccc(OC(F)(F)F)c(Cl)c1
HCID69083764

未命名化合物

PROCEDURE

实验过程

Prepared according to the described general procedure 4 (GP4) by reaction of 6-(2,6-dimethoxyphenyl)piperidin-2-one with commercially available 4-(bromomethyl)-2-chloro-1-(trifluoromethoxy)benzene. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions E): tR=0.83 min.; [M+H]+: 444.11 g/mol.

WORKUP

后处理

  1. customPrepared
  2. customSubsequent purification by preparative HPLC
  3. customafforded the target compound