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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 594603Generated: October 30, 2026

HCID 69081634, compound → HCID 69084623, compound

https://huagongshe.com/reaction/594603

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69081634HCID 69081634—
Reactant6-(2,6-Dimethoxyphenyl)piperidin-2-oneHCID 69082526—
ProductHCID 69084623HCID 69084623—

Reaction Steps

Prepared according to the described general procedure 4 (GP4) by reaction of 6-(2,6-dimethoxyphenyl)piperidin-2-one with 5-(1-bromoethyl)-3-chloro-2-(difluoromethoxy)pyridine. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.89 min., [M+H]+: 441.23 g/mol; tR=0.91 min., [M+H]+: 441.22 g/mol (diastereomers).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09242970B2
Source datasetuspto-grants-2016_01
ORD IDord-521f3ad661ff43ca86f085d203d2e7bd
Source noteuspto-grants-2016_01