HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 69081634, compound → HCID 69084623, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 69081634 | HCID 69081634 | — |
| Reactant | 6-(2,6-Dimethoxyphenyl)piperidin-2-one | HCID 69082526 | — |
| Product | HCID 69084623 | HCID 69084623 | — |
Reaction Steps
Prepared according to the described general procedure 4 (GP4) by reaction of 6-(2,6-dimethoxyphenyl)piperidin-2-one with 5-(1-bromoethyl)-3-chloro-2-(difluoromethoxy)pyridine. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.89 min., [M+H]+: 441.23 g/mol; tR=0.91 min., [M+H]+: 441.22 g/mol (diastereomers).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242970B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-521f3ad661ff43ca86f085d203d2e7bd |
| Source note | uspto-grants-2016_01 |