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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 594627Generated: October 31, 2026

Bromomethylcyclopropane → HCID 69081956, compound

https://huagongshe.com/reaction/594627

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromomethylcyclopropaneHCID 81503—
ReactantHCID 69083694HCID 69083694—
ProductHCID 69081956HCID 69081956—

Reaction Steps

Prepared according to the described general procedure 7 (GP7) by O-alkylation of 6-(2-hydroxy-6-methoxyphenyl)-1-(4-(trifluoromethoxy)benzyl)piperidin-2-one with commercially available (bromomethyl)cyclopropane. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions E): tR=0.86 min.; [M+H]+: 449.76 g/mol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09242970B2
Source datasetuspto-grants-2016_01
ORD IDord-52756248d1614712be81a26378b1ffba
Source noteuspto-grants-2016_01