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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 594629Generated: October 30, 2026

3-Chloro-1,2-propanediol → HCID 69081715, compound

https://huagongshe.com/reaction/594629

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-1,2-propanediolHCID 7290—
ReactantHCID 69083694HCID 69083694—
ProductHCID 69081715HCID 69081715—

Reaction Steps

Prepared according to the described general procedure 7 (GP7) by O-alkylation of 6-(2-hydroxy-6-methoxyphenyl)-1-(4-(trifluoromethoxy)benzyl)piperidin-2-one with commercially available 3-chloropropane-1,2-diol. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions E): tR=0.73 min.; [M+H]+: 470.28 g/mol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09242970B2
Source datasetuspto-grants-2016_01
ORD IDord-d82ae7f44a23423ba44bf561af74fb44
Source noteuspto-grants-2016_01