HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(5-Methylthiazol-2-yl)benzaldehyde → 6-(2-Methoxynaphthalen-1-yl)-1-(3-(5-methylthiazol-2-yl)benzyl)piperidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(5-Methylthiazol-2-yl)benzaldehyde | HCID 53273723 | — |
| Reactant | Methyl 5-amino-5-(2-methoxynaphthalen-1-yl)pentanoate | HCID 69082274 | — |
| Product | 6-(2-Methoxynaphthalen-1-yl)-1-(3-(5-methylthiazol-2-yl)benzyl)piperidin-2-one | HCID 69083264 | — |
Reaction Steps
Prepared according to general procedure 1 (GP1) using methyl 5-amino-5-(2-methoxynaphthalen-1-yl)pentanoate and 3-(5-methylthiazol-2-yl)benzaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.92 min.; [M+H]+: 443.13 g/mol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242970B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-70ad9b75580743e28d59837628cef057 |
| Source note | uspto-grants-2016_01 |