Hydrochloric Acid → HCID 68065988, compound

HRID 594947Notes

Reaction equation

HRID 594947 reaction equation
C(O)C.[N:4]1[CH:5]=[CH:6][N:7]2[CH:12]=[C:11]([C:13]3[C:17]4[CH2:18][N:19](C(OC(C)(C)C)=O)[CH2:20][CH2:21][C:16]=4[NH:15][N:14]=3)[CH:10]=[CH:9][C:8]=12.Cl>O1CCOCC1>[N:4]1[CH:5]=[CH:6][N:7]2[CH:12]=[C:11]([C:13]3[C:17]4[CH2:18][NH:19][CH2:20][CH2:21][C:16]=4[NH:15][N:14]=3)[CH:10]=[CH:9][C:8]=12

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 702Ethanol2×HCID 68065989HCID 68065989, compound

Product 1

HCID 68065988HCID 68065988, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

In a flask, ethanol (1 mL) was added to tert-butyl 3-(imidazo[1,2-a]pyridin-6-yl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate (0.750 g, 0.0022 mol). Hydrochloric acid in dioxane (4 M, 8 mL) was added to the reaction and was stirred for 30 minutes. Ethanol (5 mL) was added to the reaction, and the resulting solution was concentrated in vacuo. The crude product was progressed to the next step without further purification.

Workup

  1. concentrationthe resulting solution was concentrated in vacuo
  2. customThe crude product was progressed to the next step without further purification

Sources & evidence

ORD record
ord-e429da4b082344478720ab47bfa103fd
Source dataset
uspto-grants-2016_01
Patent number
US09242981B2

Reaction notes

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