Acetic Acid → HCID 89494565, compound

Participants

Reaction Steps

2-(ethylthio)-5-methylthieno[3,4-d]pyrimidin-4(3H,5H,7H)-one (4.0 g, 17.5 mmol), was suspended in 4.0 mL of conc. HCl and 6.0 mL of glacial acetic acid and the suspension heated at reflux overnight. The mixture was cooled and the precipitated solid collected by filtration, washed with water, and dried to provide 5-methylthieno[3,4-d]pyrimidine-2,4(1H,3H,5H,7H)-dione as a white solid (3.20 g, 100%).

Provenance & Evidence