反应详情

To tert-butyl 3-(6-amino-5-bromopyridin-3-yl)pyrrolidine-1-carboxylate (65 mg, 0.171 mmol) in DCM (2.4 mL) was added TFA (0.6 mL, 7.79 mmol). The reaction mixture was stirred at room temperature for 45 min. The reaction mixture was evaporated in vacuo after dilution with toluene. The crude product was used for next step without purification. The crude yield was quantitative. LCMS (m/z): 242.1/244.1 (MH+), 0.214 min.

1. customThe reaction mixture was evaporated in vacuo after dilution with toluene
2. customThe crude product was used for next step without purification
3. customThe crude yield
4. custom242.1/244.1 (MH+), 0.214 min.