HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 118045314, compound → HCID 118046325, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 118045314 | HCID 118045314 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 118046325 | HCID 118046325 | — |
Reaction Steps
To a solution of 5-(3-(benzyloxy)prop-1-en-2-yl)pyrazin-2-amine (91 mg, 0.377 mmol) in methanol (3771 μL) was added Pd/C (40.1 mg, 0.377 mmol) at room temperature. The reaction mixture was stirred at room temperature under hydrogen balloon for overnight. The reaction mixture was filtered through Celite, washed with methanol and EtOAc. The crude material was used in next step reaction without purification. LCMS (m/z): 244.2 (MH+), 0.62 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242996B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-ec6cc320a3ef4a5ab16eee530a1d46b0 |
| Source note | uspto-grants-2016_01 |