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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 595896Generated: October 30, 2026

HCID 118045314, compound → HCID 118046325, compound

https://huagongshe.com/reaction/595896

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 118045314HCID 118045314—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 118046325HCID 118046325—

Reaction Steps

To a solution of 5-(3-(benzyloxy)prop-1-en-2-yl)pyrazin-2-amine (91 mg, 0.377 mmol) in methanol (3771 μL) was added Pd/C (40.1 mg, 0.377 mmol) at room temperature. The reaction mixture was stirred at room temperature under hydrogen balloon for overnight. The reaction mixture was filtered through Celite, washed with methanol and EtOAc. The crude material was used in next step reaction without purification. LCMS (m/z): 244.2 (MH+), 0.62 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09242996B2
Source datasetuspto-grants-2016_01
ORD IDord-ec6cc320a3ef4a5ab16eee530a1d46b0
Source noteuspto-grants-2016_01