Nitric Acid → HCID 12251438, compound

HRID 596282Notes

Reaction equation

HRID 596282 reaction equation
[CH2:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][C:2]21[CH2:14][CH2:13][C:12](=[O:15])[CH2:11][CH2:10]2.[N+:16]([O-])([OH:18])=[O:17]>FC(F)(F)C(O)=O>[N+:16]([C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[CH2:3][C:2]1([CH2:14][CH2:13][C:12](=[O:15])[CH2:11][CH2:10]1)[CH2:1]2)([O-:18])=[O:17]

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 12251437HCID 12251437, compound

Product 1

HCID 12251438HCID 12251438, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

A spiro(cyclohexane-1,2'-indan)-4-one [11] [prepared as above in step (10) of the first process for producing the compounds of Process B] in the cold (at about 0° C.) in trifluoroacetic acid, has nitric acid added thereto and the low temperature maintained for from about 1 to about 4 hours, to yield a corresponding 5'-nitrospiro(cyclohexane-1,2'-indan)-4-one [29] .

Workup

  1. additionadded
  2. temperaturethe low temperature maintained for from about 1 to about 4 hours

Sources & evidence

ORD record
ord-ae9029d9db1a4901b87897a80b63288a
Source dataset
uspto-grants-1977_03
Patent number
US04010201

Reaction notes

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