HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Pyrimidinyl)piperazine → 1-(2-Pyrimidyl)piperazine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Pyrimidinyl)piperazine | HCID 88747 | — |
| Reactant | HCID 54430147 | HCID 54430147 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | 1-(2-Pyrimidyl)piperazine hydrochloride | HCID 2818457 | — |
Reaction Steps
A solution of 8.5 g (0.0344 mole) of 5-chloromethyl-2-phenyl benzo [d]-1,3-dioxole (BP/0.05 mm = 135°-137° C) and 11.3 g (0.0689 mole) of 1-(2-pyrimidinyl) piperazine in 250 ml of anhydrous xylene was refluxed for 9 hours. The precipitate of 1-(2-pyrimidinyl) piperazine hydrochloride formed was suction-filtered off and the xylene was evaporated off under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04010267 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-380b7b33d57149dfa0429afb77893c1b |
| Source note | uspto-grants-1977_03 |