HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetyl chloride → HCID 21450834, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetyl chloride | HCID 6577 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | HCID 21450815 | HCID 21450815 | — |
| Product | HCID 21450834 | HCID 21450834 | — |
Reaction Steps
In the manner given in Preparation 10, 6-(trifluoromethyl)-5-(o-fluorophenyl)-3H-1,4-benzodiazepin-2-yl hydrazine is reacted with chloroacetyl chloride and after 1.5 hours with sodium acetate, then refluxed to give 1-(chloromethyl)-7-(trifluoromethyl)-6-(o-fluorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04010177 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-c5a0069cabe949d3944bcff57b23190f |
| Source note | uspto-grants-1977_03 |