HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → HCID 21437268, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | 8-chloro-1-(chloromethyl)-6-(o-chlorophenyl)-4H-s-triazolo-[4,3-a][1,4]benzodiazepine | HCID 12612348 | — |
| Reactant | (Cyclopropylmethyl)methylamine | HCID 12919209 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 21437268 | HCID 21437268 | — |
Reaction Steps
In the manner given in Preparation 29, potassium iodide and 8-chloro-1-(chloromethyl)-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine in tetrahydrofuran are treated with methyl(cyclopropylmethyl)amine to give 8-chloro-1-[[(cyclopropylmethyl)methylamino]methyl]-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]-benzodiazepine. Preparation 31 8-Bromo-1-[[(cyclopropylemethyl)ethylamino]methyl]-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04010177 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-fb6b88cb407842cc85e1b26230298c5a |
| Source note | uspto-grants-1977_03 |