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HRID596382

反应详情

EQUATION

反应方程式

HRID 596382 的结构方程式

REACTANTS

反应物

3
结构：[I-].[K+]
HCID4875

Potassium iodide

IK

结构：CC=CCN
HCID30447

But-2-en-1-amine

C4H9N

结构：FC(F)(F)c1ccc2c(c1)C(c1ccccc1Cl)=NCc1nnc(CCl)n1-2
HCID21330780

未命名化合物

PRODUCTS

生成物

1
结构：C=CCCNCc1nnc2n1-c1ccc(C(F)(F)F)cc1C(c1ccccc1Cl)=NC2
HCID68120042

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

In the manner given in Preparation 39, 8-(trifluoromethyl)-1-(chloromethyl)-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine, potassium iodide and methylallylamine in tetrahydrofuran are reacted to give 8-(trifluoromethyl)-1-[(allylmethylamino)methyl]-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine. Preparation 44 8-Chloro-1-[(allylpropylamino)methyl]-6-(2,6-difluorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine

WORKUP

后处理

  1. customare reacted