Potassium Iodide → HCID 68120199, compound

HRID 596384Notes

Reaction equation

HRID 596384 reaction equation
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]2[N:13]3[C:14]([CH2:17]Cl)=[N:15][N:16]=[C:12]3[CH2:11][N:10]=[C:9]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[C:8]=2[CH:25]=1)([O-:3])=[O:2].[I-].[K+].[CH2:28]([CH:31]=[CH:32][CH2:33][NH2:34])[CH2:29][CH3:30]>O1CCCC1>[N+:1]([C:4]1[CH:5]=[CH:6][C:7]2[N:13]3[C:14]([CH2:17][NH:34][CH2:33][CH2:32][CH2:31][CH2:28][CH:29]=[CH2:30])=[N:15][N:16]=[C:12]3[CH2:11][N:10]=[C:9]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[C:8]=2[CH:25]=1)([O-:3])=[O:2]

Participants

5

Reactant 3

HCID 4875Potassium IodideHCID 20291837HCID 20291837, compoundHCID 53415109Hex-2-en-1-amine

Product 1

HCID 68120199HCID 68120199, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

In the manner given in Preparation 39, 8-nitro-1-(chloromethyl)-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine, potassium iodide and propylallylamine in tetrahydrofuran are reacted to give 8-nitro-1-[(allylpropylamino)methyl]-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine. Preparation 46 8-Fluoro-1-[(allylethylamino)methyl]-6-(o-fluorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine

Workup

  1. customare reacted

Sources & evidence

ORD record
ord-9a536ceac2a4423cb71de7d96bdd70b1
Source dataset
uspto-grants-1977_03
Patent number
US04010177

Reaction notes

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