HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Toluenesulfonyl chloride → HCID 21450857, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| Reactant | Propargylamine | HCID 239041 | — |
| Reactant | HCID 21450805 | HCID 21450805 | — |
| Product | HCID 21450857 | HCID 21450857 | — |
Reaction Steps
In the manner given in Example 47, 5-chloro-2',6'-difluoro-2-[3-(hydroxymethyl)-5-[(dimethylamino)methyl]-4H-1,2,4-triazol-4-yl]benzophenone is treated first with p-toluenesulfonyl chloride followed by propargylamine, to give 5-chloro-2',6'-difluoro-2-[3-[[(2-propynyl)amino]methyl]-5-[(dimethylamino)methyl]-4H-1,2,4-triazol-4-yl]benzophenone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04010177 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-3135e56a0fc7490b91e1cd8ff61b1728 |
| Source note | uspto-grants-1977_03 |