HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonyl chloride → HCID 21450841, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | Propargylamine | HCID 239041 | — |
| Reactant | [5-Chloro-2-[3-[(dimethylamino)methyl]-5-(hydroxymethyl)-4H-1,2,4-triazol-4-yl]phenyl]phenylmethanone | HCID 21450879 | — |
| Product | HCID 21450841 | HCID 21450841 | — |
Reaction Steps
In the manner given in Example 47, 5-chloro-2-[3-(hydroxymethyl)-5-[(dimethylamino)methyl]-4H-1,2,4-triazol-4-yl]benzophenone is treated first with methanesulfonyl chloride followed by propargylamine to give 5-chloro-2-[3-[[(2-propynyl)amino]methyl]-5-[(dimethylamino)methyl]-4H-1,2,4-triazol-4-yl]benzophenone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04010177 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-00d6dd83ac054661a5c3c5d987ee6d9f |
| Source note | uspto-grants-1977_03 |