Sodium Bicarbonate → HCID 21246538, compound

HRID 596423Notes

Reaction equation

HRID 596423 reaction equation
[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[C:6]1([N+:12]2[C:17](Cl)=[CH:16][C:15]([NH2:19])=[CH:14][N:13]=2)[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.C(=O)(O)[O-].[Na+].[H][H]>[Ni].O>[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[C:6]1([N+:12]2[CH:17]=[CH:16][C:15]([NH2:19])=[CH:14][N:13]=2)[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1

Participants

6

Reactant 3

HCID 516892Sodium BicarbonateHCID 21449817HCID 21449817, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 21246538HCID 21246538, compoundYield 86.7%

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 962WaterSolvent

Procedure

20.3 parts of 1-phenyl-4-amino-6-chloropyridazinium perchlorate, 200 parts of water, 10parts of sodium bicarbonate and about 5 parts of Raney nickel are stirred for about three hours and in an autoclave at 20° to 25° C and a hydrogen pressure of 200 atmospheres gauge. The reaction solution is filtered from catalyst and evaporated. The crystalline residue is washed with a little water. 15.6 parts (86.7% of theory) of 1-phenyl-4-aminopyridazinium perchlorate is obtained; C10H10O4N3Cl, melting point 184° to 186° C after having been recrystallized from methanol.

Workup

  1. filtrationThe reaction solution is filtered from catalyst
  2. customevaporated
  3. washThe crystalline residue is washed with a little water

Sources & evidence

ORD record
ord-ab6efe9ee89b439dbbee27648a29276c
Source dataset
uspto-grants-1977_03
Patent number
US04011220

Reaction notes

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