Acetonitrile → HCID 86733971, compound

HRID 596428Notes

Reaction equation

HRID 596428 reaction equation
[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[CH3:6][N+:7]1[C:12](Cl)=[CH:11][C:10]([NH2:14])=[CH:9][N:8]=1.C(#N)C.[CH2:18]([SH:20])[CH3:19]>C(N(CC)CC)C>[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[CH3:6][N+:7]1[C:12]([S:20][CH2:18][CH3:19])=[CH:11][C:10]([NH2:14])=[CH:9][N:8]=1

Participants

5

Reactant 3

HCID 6342AcetonitrileHCID 6343EthanethiolHCID 21449765HCID 21449765, compound

Product 1

HCID 86733971HCID 86733971, compoundYield 67.9%

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

24.4 parts of 1-methyl-4-amino-6-chloropyridazinium perchlorate in 250 parts of acetonitrile is stirred with 10 parts of ethylmercaptan and 10 parts of triethylamine for four hours at 50° to 60° C. After the solvent has been distilled off the residue is washed with 100 parts of water. 18.3 parts (67.9% of theory) of 1-methyl-4-amino-6-ethylmercaptopyridazinium perchlorate is obtained; C7H12O4N3SCl, melting point 136° to 137° C after having been recrystallized from alcohol.

Workup

  1. distillationAfter the solvent has been distilled off the residue
  2. washis washed with 100 parts of water

Sources & evidence

ORD record
ord-3e0a76832dbc499e8ff8d678d85043dc
Source dataset
uspto-grants-1977_03
Patent number
US04011220

Reaction notes

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