Sulfuric Acid → HCID 178514941, compound

Participants

Reaction Conditions

Reaction Steps

103 g. of o-(3-hydroxy-1-isoquinolinyl)-benzoic acid were dispersed in 310 ml. of 96% H2SO4. This dispersion was then heated to 130° C. and kept under stirring at that temperature for 1 hour. The reaction mass was then cooled to about 90° C. and was then carefully poured into about 20 liters of hot water at 90°-95° C. The reaction mass was then stirred for 1 hour while leaving it to cool down.

Provenance & Evidence