Hydrochloric Acid → 1-(3-Chlorophenyl)-3-[1-(3,3-dimethylazetidin-1-yl)propan-2-yl]-4-methylimidazolidin-2-one

HRID 596465Notes

Reaction equation

HRID 596465 reaction equation
[CH3:1][C:2]1([CH3:6])[CH2:5][NH:4][CH2:3]1.Cl[CH2:8][CH:9]([N:11]1[CH:15]([CH3:16])[CH2:14][N:13]([C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([Cl:23])[CH:18]=2)[C:12]1=[O:24])[CH3:10].Cl>>[Cl:23][C:19]1[CH:18]=[C:17]([N:13]2[CH2:14][CH:15]([CH3:16])[N:11]([CH:9]([CH3:10])[CH2:8][N:4]3[CH2:5][C:2]([CH3:6])([CH3:1])[CH2:3]3)[C:12]2=[O:24])[CH:22]=[CH:21][CH:20]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 12674605HCID 12674605, compoundHCID 12674607HCID 12674607, compound

Product 1

HCID 30402931-(3-Chlorophenyl)-3-[1-(3,3-dimethylazetidin-1-yl)propan-2-yl]-4-methylimidazolidin-2-one

Procedure

The title compound is prepared pursuant to the procedure of Example 4 from 3,3-dimethylazetidine and 3-(2-chloro-1-methylethyl)-1-(m-chlorophenyl)-4-methyl-2-imidazolidinone. B.p. 200° C./0.6 mm Hg. The corresponding hydrochloride melts at 162°-164° C.

Sources & evidence

ORD record
ord-f69a0324bc974d8f964f0cb5b12448aa
Source dataset
uspto-grants-1977_03
Patent number
US04011238

Reaction notes

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