N-(2-Aminoethyl)piperidine → N-(2-Diethylaminoethyl)-N'-(2-piperidinoethyl)-thiourea

HRID 596594Notes

Reaction equation

HRID 596594 reaction equation
[NH2:1][CH2:2][CH2:3][N:4]1[CH2:9][CH2:8][CH2:7][CH2:6][CH2:5]1.[CH2:10]([N:12]([CH2:15][CH2:16][N:17]=[C:18]=[S:19])[CH2:13][CH3:14])[CH3:11]>>[CH2:10]([N:12]([CH2:13][CH3:14])[CH2:15][CH2:16][NH:17][C:18]([NH:1][CH2:2][CH2:3][N:4]1[CH2:9][CH2:8][CH2:7][CH2:6][CH2:5]1)=[S:19])[CH3:11]

Participants

3

Reactant 2

HCID 33944N-(2-Aminoethyl)piperidineHCID 2772281Diethyl(2-isothiocyanatoethyl)amine

Product 1

HCID 21450384N-(2-Diethylaminoethyl)-N'-(2-piperidinoethyl)-thiourea

Procedure

By the general method described in Example 1, 1-(2-aminoethyl)-piperidine is reacted with diethylaminoethyl isothiocyanate to give the title compound.

Sources & evidence

ORD record
ord-ade971e977d14b12ac83d1471f868058
Source dataset
uspto-grants-1977_03
Patent number
US04011331

Reaction notes

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