反应详情

A mixture of 2.0 g. of 6-amino-3,4-ethylenedioxybenzoic acid methyl ester and 6 ml. of 99% formamide is refluxed for 1.5 hours, then cooled, diluted with 5 ml. of water and the resulting precipitate filtered off, water washed and dried to obtain 6,7-ethylenedioxyquinazolin-4(3H)-one, m.p. 275° C.

1. additionA mixture of 2.0 g
2. temperaturecooled
3. additiondiluted with 5 ml
4. filtrationof water and the resulting precipitate filtered off
5. washwater washed
6. customdried