HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formamide → 7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4(3H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formamide | HCID 713 | — |
| Reactant | Methyl 7-amino-2,3-dihydro-1,4-benzodioxin-6-carboxylate | HCID 3146109 | — |
| Product | 7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4(3H)-one | HCID 135736599 | — |
Reaction Steps
A mixture of 2.0 g. of 6-amino-3,4-ethylenedioxybenzoic acid methyl ester and 6 ml. of 99% formamide is refluxed for 1.5 hours, then cooled, diluted with 5 ml. of water and the resulting precipitate filtered off, water washed and dried to obtain 6,7-ethylenedioxyquinazolin-4(3H)-one, m.p. 275° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04011323 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-db09790bee9b48718e3171bffd3523fc |
| Source note | uspto-grants-1977_03 |