反应详情

A mixture of 14.6 g. of 2-amino-5-dimethylaminobenzoic acid and 75 ml. of formamide is refluxed for 40 minutes, cooled to room temperature, 100 ml. of water added, the crystals broken up and recovered by filtering. After washing several times with water, the solids are dried to obtain 6-dimethylamino-quinazolin-4(3H)one, m.p. 233°-236° C.

1. additionA mixture of 14.6 g
2. customrecovered
3. filtrationby filtering
4. washAfter washing several times with water
5. customthe solids are dried