反应详情

A mixture of 10.6 g of (0.031 mole) of 5-tetradecyloxy-2-thiophenecarboxylic acid, 200 ml of acetone, and 4.3 g (0.031 mole) of potassium carbonate is stirred at room temperature after which 3.9 g (0.031 mole) of dimethyl sulfate is added. The mixture is stirred with heating for about 21/2 hours during which time 10 ml of methanol is added. The mixture is then diluted with 100 ml of acetone and filtered. The filtrate is evaporated to dryness to give 5-tetradecyloxy-2-thiophenecarboxylic acid methyl ester.

1. additionis added
2. additionis added
3. filtrationfiltered
4. customThe filtrate is evaporated to dryness