Hydrochloric Acid → HCID 13530371, compound

HRID 596671Notes

Reaction equation

HRID 596671 reaction equation
Cl.[OH:2][C:3]1[CH:15]=[CH:14][CH:13]=[CH:12][C:4]=1[C:5]([CH2:7][CH2:8][C:9]([OH:11])=[O:10])=[O:6].[CH3:16]O>>[OH:2][C:3]1[CH:15]=[CH:14][CH:13]=[CH:12][C:4]=1[C:5]([CH2:7][CH2:8][C:9]([O:11][CH3:16])=[O:10])=[O:6]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 30160863-(2-Hydroxybenzoyl)propionic acid

Product 1

HCID 13530371HCID 13530371, compoundYield 98%

Procedure

Hydrogen chloride was bubbled into a gently boiling solution of the known 3-(2-hydroxybenzoyl)propionic acid (10 g, 0.05 mole) in dry methanol (20 ml) until esterification was complete. The solution was poured into ice-water and the ester extracted into dichloromethane. The organic solution was washed with water and evaporated to give methyl 3-(2-hydroxybenzoyl)propionate (10.55 g, 98%) as a pale yellow oil.

Workup

  1. extractionthe ester extracted into dichloromethane
  2. washThe organic solution was washed with water
  3. customevaporated

Sources & evidence

ORD record
ord-fb93d97fe3944f93854ea89779a69caa
Source dataset
uspto-grants-1977_03
Patent number
US04011321

Reaction notes

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