Hydrogen Bromide → HCID 20360782, compound
Reaction equation
C([O:8][C:9]1[CH:10]=[C:11]([CH:19]=[CH:20][C:21]=1[C:22]#[N:23])[C:12]([CH2:14][CH2:15][C:16]([OH:18])=[O:17])=[O:13])C1C=CC=CC=1.Br>C(O)(=O)C>[C:22]([C:21]1[CH:20]=[CH:19][C:11]([C:12]([CH2:14][CH2:15][C:16]([OH:18])=[O:17])=[O:13])=[CH:10][C:9]=1[OH:8])#[N:23]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
3-(3-Benzyloxy-4-cyanobenzoyl)propionic acid was warmed with 33% hydrogen bromide in acetic acid and the solution was poured into ice-water to give 3-(4-cyano-3-hydroxybenzoyl)propionic acid.
Sources & evidence
- ORD record
- ord-1265c726ef85470a901d3a7cec0f83d9
- Source dataset
- uspto-grants-1977_03
- Patent number
- US04011321
Reaction notes
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