Acetyl chloride → HCID 20370071, compound

Participants

Reaction Steps

Repeating the procedure of Example 1, step B, but replacing the p-thiomethylphenyl)-acetyl chloride, used therein, with an approximately equivalent amount of 3-(p-fluorophenyl)-3-methyl-butyryl chloride, there is accordingly obtained ethyl 5-(p-fluorophenyl)-2,5-dimethyl-hexa-2,3-dienoate, which upon treatment according to Example 2, yields 5-(p-fluorophenyl)-2,5-dimethyl-hexa-2,3-dienoic acid, m.p. (72.5° - 75.5°).

Provenance & Evidence