Bromomethyl 4-methoxyphenyl ketone → HCID 45047818, compound

HRID 596718Notes

Reaction equation

HRID 596718 reaction equation
CO[C:3]1[CH:12]=[CH:11][C:6]([C:7](=[O:10])[CH2:8][Br:9])=[CH:5][CH:4]=1.C(Br)C(C1C=CC=CC=1)=O.[C:23]([C:26]1[CH:31]=[CH:30][N:29]=[CH:28][CH:27]=1)(=[O:25])[CH3:24]>N1C=CC=CC=1>[Br-:9].[CH2:8]([N+:29]1[CH:30]=[CH:31][C:26]([C:23](=[O:25])[CH3:24])=[CH:27][CH:28]=1)[C:7]([C:6]1[CH:5]=[CH:4][CH:3]=[CH:12][CH:11]=1)=[O:10]

Participants

5

Reactant 3

HCID 4965Bromomethyl 4-methoxyphenyl ketoneHCID 6259Phenacyl bromideHCID 142824-Acetylpyridine

Product 1

HCID 45047818HCID 45047818, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Employing the procedure of Example I above but replacing 4-methoxyphenacyl bromide with a substantially equimolecular amount of phenacyl bromide and replacing pyridine with a substantially equimolecular amount of 4-acetylpyridine there is obtained N-(phenacyl) 4-acetylpyridinium bromide, a white solid melting at 214-215° C., and which is soluble in water.

Sources & evidence

ORD record
ord-7ede73ee986c417bb3757261f71ae2b9
Source dataset
uspto-grants-1977_03
Patent number
USRE029153

Reaction notes

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