Hydrochloric Acid → HCID 178486336, compound

HRID 596799Notes

Reaction equation

HRID 596799 reaction equation
[C:1]([C:9]1[C:18]([CH2:19][O:20]C(=O)C)=[N+:17]([O-:24])[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[N+:10]=1[O-:25])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[CH3:27]O>>[CH3:27][O:8][C:1]1([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[C:9]2=[N+:10]([O-:25])[C:11]3[C:16]([N+:17]([O-:24])=[C:18]2[CH2:19][O:20]1)=[CH:15][CH:14]=[CH:13][CH:12]=3

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 178475874HCID 178475874, compound

Product 1

HCID 178486336HCID 178486336, compoundYield 61%

Procedure

A stirred suspension of 0.50 g. (1.47 mmol.) of 2-benzoyl-3-acetoxymethylquinoxaline 1,4-dioxide in 10 ml. of methanol was saturated with dry hydrogen chloride. The reaction mixture was stirred at room temperature for three days and then the suspended solid was removed by filtration. The solid was washed with methanol, and dried, to give 0.28 g. (61% yield) of 1-methoxy-1-phenyl-1,3-dihydrofuro[3,4-b]quinoxaline 4,9-dioxide, m.p. 153 °-155° C.

Workup

  1. additionA stirred suspension of 0.50 g
  2. customthe suspended solid was removed by filtration
  3. washThe solid was washed with methanol
  4. customdried
  5. customto give 0.28 g

Sources & evidence

ORD record
ord-1d58b3f316cb42e4814c8ee4be217a19
Source dataset
uspto-grants-1977_03
Patent number
US04012385

Reaction notes

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