1-(3',4',5'-Trimethoxy benzyl)-2-phenyl-3-keto piperazine → 1-(3',4',5'-Trimethoxy benzyl)-2-phenyl piperazine

Participants

Reaction Steps

1-(3',4',5'-Trimethoxy benzyl)-2-phenyl-3-keto piperazine prepared according to Example 13, is reduced by following the procedure described hereinabove in Example 8 (a) whereby, in place of 1-diethylamino ethyl-3-keto-2-phenyl piperazine, the equimolecular amount of said 1-(3',4',5'-trimethoxy benzyl-2-phenyl-3-keto piperazine is used. The resulting 2-phenyl piperazine compound is obtained in the form of a yellow oil boiling at 185-195° C./0.08 mm. Hg.

Provenance & Evidence