Hydrochloric Acid → HCID 21448647, compound

HRID 596868Notes

Reaction equation

HRID 596868 reaction equation
[CH2:1]([CH:8]1[C:13]([CH3:15])([CH3:14])[C:12](=[O:16])[CH:11](C(OCC)=O)[CH2:10][N:9]1[CH3:22])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.N1CCCCC1=O.[ClH:30]>>[ClH:30].[CH2:1]([CH:8]1[C:13]([CH3:15])([CH3:14])[C:12](=[O:16])[CH2:11][CH2:10][N:9]1[CH3:22])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 313Hydrochloric Acid3×HCID 126652-PiperidoneHCID 21448608HCID 21448608, compound

Product 1

HCID 21448647HCID 21448647, compoundYield 75%

Procedure

A solution of 217 g of the hydrochloride of ethyl 2-benzyl-4-oxo-1,3,3-trimethyl-5-piperidine carboxylate in 6 N hydrochloric acid is refluxed for 40 minutes. The piperidone is gathered as the hydrochloride in the same way as described in example 12. Yield 75%; melting point 177° - 179° C, with decomposition.

Sources & evidence

ORD record
ord-41ef08adec804d90a31d9503762602fb
Source dataset
uspto-grants-1977_03
Patent number
US04012392

Reaction notes

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