反应详情

A mixture of 4-ethyl-3-methylphenol (31.51 g) and anhydrous potassium carbonate (91.25 g) was heated at 175° for 4 hours under a carbon dioxide pressure of 1,300 p.s.i. The cooled reaction products were dissolved in water (2 l). Acidification with hydrochloric acid, filtration and recrystallisation of the solid from ethanol-water gave 5-ethyl-4-methylsalicylic acid, m.p. 152.5°-154° C. (Found; C, 66.55; H, 6.71; C10H12O3 requires; C, 66.65; H, 6.71.)

1. temperaturewas heated at 175° for 4 hours under a carbon dioxide pressure of 1,300 p.s.i
2. customThe cooled reaction products
3. filtrationAcidification with hydrochloric acid, filtration and recrystallisation of the solid from ethanol-water